Production line

Infrastructure and Facilities

Production Areas:

  • Cleanroom Space: 400 square meters of cleanroom area.
  • Cold Storage: Cold storage facility with a capacity of 200 cubic meters.
  • Facilities and Warehouse: 2,000 square meters of storage area equipped with advanced
    preservation and storage systems, along with a Purified Water System to meet production requirements

Laboratories:

  • Quality Control Laboratory: Equipped with state-of-the-art equipment for quality control
    of intermediate and final products.
  • Animal Laboratory: Equipped with dedicated isolators for conducting scientific research
    and product development, particularly in the areas of safety testing and vaccine efficacy.

Production process

Quality standards:

  • Class B (Full Fresh) to Grade A Conversion with Ceiling Hoods: The units dedicated to
    antigen production, formulation, and final product filling initially operate in Class B
    areas. By employing full fresh exhaust air systems and Class A biological safety cabinets, the environment is upgraded to Grade A, ensuring superior sanitary conditions and high quality standards for production.
  • Industrial Automation Systems: The implementation of advanced automation systems
    enhances precision, improves product quality, and minimizes human error during the
    production process.
  • Washing and Sterilization Procedures: The use of Water for Injection (WFI) and Pure
    Steam is highlighted as essential for maintaining the quality and safety of the products.

Competitive advantages

High Quality products:

Advantages of Nova Vaccine Rad’s vaccines and their impact on the poultry industry:

  • Adapted to the latest circulating field strains in the country and the Middle East.
  • Produced in accordance with the World Organization for Animal Health (WOAH) Good
    Manufacturing Practices (GMP), within the country’s only biosafety level 2 (BSL-2)
    enhanced facility for poultry vaccines.
  • Contain the optimal amount of antigen in all produced vaccines.
  • The utilization of a stable, low-viscosity oil-based adjuvant, which enhances the ease of injection

Experience and Technical Expertise:

  • Highlighting the expertise and experience of the company’s technical team: Currently, 20 professionals with Master’s and PhD degrees are employed by the company.

Quality Control

Quality control tests:

  • Overview of IPQC processes:
  • Testing of fertilized eggs (including Mycoplasma testing, SAN Test: Specific Antibody Negative, and HA Test).
  • Confirmation of inactivation, sterility, and Mycoplasma for bulk antigens
  • Testing of bulk virus preparations ready for formulation.
  • HA test, sterility testing for adjuvants, vaccine vials, caps, and rubber stoppers.
  • Collaboration with the Veterinary Faculty of Tehran University’s Industry Liaison
    Office, partner laboratories of the Iranian Food and Drug Organization and the Iranian Veterinary Organization.
  • Final verification: Essential testing of the final vaccine product before distribution
    to ensure its quality and safety